Table 2.
Comparison of laboratory tests in patients with COVID-19 on admission to hospital.
| Item (unit, normal range) | Overall(n=239), Median (IQR) | Ordinary group(n=176), Median (IQR) | Severe/critical group(n=63), Median (IQR) | p Value |
|---|---|---|---|---|
| Blood routine | ||||
| WBC count(×109·L-1，3.5~9.5) | 5.4 (4.1~6.8) | 4.9 (4.0~5.9) | 6.5 (5.1~11.5) | 0.003 |
| NEU% (40~75) | 68.3 (56.8~78.8) | 61.6 (51.8~72.4) | 84.2 (75.1~91.2) | < 0.001 |
| NEU count(×109·L-1，1.8~6.3) | 3.4 (2.2~5.2) | 2.8 (2.0~4.0) | 5.5 (3.8~10.8) | < 0.001 |
| LYM % (20~50) | 23.5 (13.3~34.2) | 28.0 (20.4~37.4) | 9.9 (6.4~19.3) | < 0.001 |
| LYM count(×109·L-1，1.1~3.2) | 1.1 (0.7~1.5) | 1.3 (0.9~1.7) | 0.7 (0.4~1.1) | < 0.001 |
| PLT(×109·L-1，125~350) | 164(133~218) | 163(140~216) | 182(129~227) | 0.717 |
| Indicators of inflammation | ||||
| CRP (mg· L-1, 0~8) | 13.6 (3.7~34.1) | 5.6 (0.8~21.4) | 36.9 (19.3~96.1) | < 0.001 |
| PCT < 0.5, (n, %) | 78.0 (98.7) | 55.0(100) | 23.0 (95.8) | 0.304 |
| Coagulation | ||||
| PT(s，9.5~14.5) | 14.3 (13.4~15.9) | 14.4 (13.5~16.0) | 14.3 (13.3~15.0) | 0.713 |
| D-Dimer (μg·mL~1, 0~1.1) | 0.22 (0.14~0.35) | 0.19 (0.09~0.26) | 0.45 (0.22~0.64) | < 0.001 |
| Myocardial enzymes | ||||
| CK (IU·L-1, 22~269) | 91.4 (54.8~158.2) | 92.7 (55.5~154.4) | 86.2 (46.0~178.1) | 0.543 |
| CK-MB (U·L-11, 0~25) | 11.1 (9.5~15.7) | 11.3 (9.4~15.8) | 11.1 (9.6~13.6) | 0.598 |
| LDH (U·L-1, 120~250) | 246 (178~306) | 202 (169~270) | 295 (265~374) | < 0.001 |
| Biochemical indicators | ||||
| ALT (IU·L-1, 9~50) | 23 (15~42) | 20 (15~35) | 29 (21~43) | 0.098 |
| AST (IU·L-1, 15~45) | 27 (21~36) | 25 (21~35) | 40 (23~37) | 0.159 |
| ALB (g·L-1, 40~55) | 42.4 (38.3~46.9) | 44.3 (41.2~47.7) | 36.3 (33.0~39.1) | < 0.001 |
| TB (umol·L-1，3.4~21) | 16.4 (11.8~21.1) | 14.7 (11.4~20.1) | 17.2 (12.9~21.3) | 0.263 |
| Cr (umol·L-1，57~111) | 69 (58~81) | 70 (59~80) | 69 (56~81) | 0.819 |
| BUN (mmol·L-1，3.1~8) | 4.0 (3.0~5.4) | 3.6 (3.0~4.5) | 5.4 (4.3~6.0) | < 0.001 |
WBC: white blood cells, NEU: neutrophils, LYM: lymphocytes, PLT: platelets, CRP: C-reactive protein, PCT: procalcitonin, PT: prothrombin time, CK: creatine kinase, CK-MB: creatine kinase isoenzyme, LDH: lactate dehydrogenas, ALT: alanine aminotransferase, AST: aspartate aminotransferase, TB: total bilirubin, Cr: creatinine, BUN: urea nitrogen.