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LRP6 rs2302685 was associated with a reduced liver injury in NAFLD patients. (A) Distribution of 22 SNPs likely contributing to the individual risk of NAFLD based on the 'two-hit hypothesis'. (B) Comparison of the serum levels of ALT and AST between the LRP6 rs2302685 T allele carriers (n=47) and C allele carriers (n=239) in NAFLD subjects.
