Table 2.

The comparison of demographics and clinical characteristics between LRP6 rs2302685 CC /CT and TT genotypes in NAFLD subjects

Characteristic	CC/CT genotype (n=47)	TT genotype (n=239)	P value
Age, year	45.8±11.26	49.62±11.54	0.019
Gender, Male/Female	32/15	141/97	0.257
BMI, kg/m2	26.94±2.22	26.11±2.6	0.030
SBP, mmHg	124.56±22.72	123.62±19.19	0.769
DBP, mmHg	84.37±14.33	84.07±15.97	0.702
WC, cm	85.26±7.53	85.45±8.51	0.960
HP, cm	96.91±5.5	95.01±6.91	0.018
TP, g/L	72.18±5.37	72.48±4.85	0.819
Albumin, g/L	45.17±4.85	44.94±4.53	0.217
Globulin, g/L	27.01±3.06	27.81±5.07	0.241
A/G	1.69±0.28	1.67±0.35	0.307
TBIL, μmol/L	13.91±8.7	12.5±5.78	0.580
DBIL, μmol/L	5.95±4.08	5.34±3.37	0.496
TBA, μmol/L	4.56±2.74	4.5±5.33	0.220
ALT, U/L	35.43±20.53	27.67±13.34	0.021
AST, U/L	38.59±16.01	27.57±13.74	0.000
FBG, mmol/L	5.21±0.61	5.63±1.77	0.557
LDL-C, mmol/L	2.97±0.89	3.16±0.83	0.140
TG, mmol/L	2.59±2.43	2.5±1.72	0.914
TC, mmol/L	5.02±1.1	5.18±1.06	0.320
HDL-C , mmol/L	1.22±0.34	1.28±0.32	0.591

Note: Values are expressed as mean±SD and compared by Student's t-test if the data is normal distribution, otherwise Mann-Whitney U test is used, except for gender that p value stands for statistical significance using Chi-square test. A P-value < 0.05 was considered as statistically significant (in bold).

Abbreviations: NAFLD, nonalcoholic fatty liver disease; BMI, Body Mass Index; SBP, systemic blood pressure; DBP, diastolic blood pressure; WC, Waist circumference; HP, Hip circumference; TP, Total Protein; A/G, the ratio of albumin to globulin; TBIL, total bilirubin; DBIL, direct bilirubin; TBA, total bile acid; ALT, glutamic-pyruvic transaminase; AST, glutamic oxalacetic transaminase; FBG, fasting blood-glucose; LDL-C, low density lipoprotein cholesterin; TG, triglyceride; TC, total cholesterol; HDL-C, high density lipoprotein cholesterol.