All patients (N = 91)
Median (range) age at rFVIIIFc start, years	6.7 (0‒17.2)
Hemophilia severity, n (%) Severe (<1 IU/dL FVIII) Moderate (1–5 IU/dL FVIII) Mild (5–40 IU/dL FVIII) Unknown	61 (67.0) 22 (24.2) 6 (6.6) 2 (2.2)
FVIII exposure prior to rFVIIIFc treatment (ED), n (%) 0 1–3 4–20 21–100 101–150 ≥151 Not available	16 (17.6) 6 (6.6) 6 (6.6) 7 (7.7) 8 (8.8) 47 (51.6) 1 (1.1)
Family history of inhibitor, n (%)	8 (8.8)

ED, exposure day; FVIII, factor VIII; rFVIIIFc, recombinant factor VIII Fc fusion protein.