Prophylaxis	On‐demand	ITI
Average Gilbert score (all joints), n	35	–	1
Mean ± SD Median (range)	1.7 ± 1.6 1.0 (0.0–5.0)	–	1.0 1.0 (1.0–1.0)
HJHS: Global Gait Score, n	86	0	8
Mean ± SD Median (range)	1.6 ± 1.6 1.0 (0.0–4.0)	–	1.8 ± 1.5 1.0 (0.0–4.0)
ABR, n	190	2	11
Mean ± SD Median (range)	3.3 ± 4.8 2.0 (0.0–30.0)	5.0 ± 7.1 5.0 (0.0–10.0)	4.0 ± 7.9 0.0 (0.0–26.0)
AJBR,† n	190	2	11
Mean ± SD Median (range)	2.2 ± 3.9 1.0 (0.0–30.0)	4.5 ± 6.4 4.5 (0.0–9.0)	2.6 ± 5.6 0.0 (0.0–19.0)

*Bleedings occurring during regimens of <90 days were not used for this analysis. Bleedings recorded at screening had occurred up to 12 months prior to screening. Patients with >1 regimen during a study year (switch patients) were counted for each regimen; bleeding events were only counted for the regimen during which they occurred.

^†Owing to missing information for joint/non‐joint classification, AJBRs may be underestimated.