Dexamethasone use	DOAC dose	Indication	New/chronic users	Age	Sex	Weight (kg)	eGFR (mL/min)	DOAC trough level (ng/mL)	DOAC peak level (ng/mL)
Yes	Apixaban 2.5 mg bid	AF AF AF	New New New	88 95 80	M M M	78 66 79	35 19 56	179 (high) 36 150	227 (high) 69 170
	Apixaban 5 mg bid	AF VTE	Chronic New	84 66	F M	109 87	80 132	122 32	182 110
	Apixaban 10 mg bid	VTE	New	82	M	69	41	192	308
	Rivaroxaban 10 mg od	Post AMI	Chronic	78	M	78	82	41 (high)	125
	Rivaroxaban 15 mg od	AF	New	86	F	67	43	52	283
	Rivaroxaban 20 mg od	AF AF AF AF	Chronic New New New	86 83 74 71	M M M M	68 90 110 116	66 89 75 90	81 64 76 26	545 (high) 306 263 158 (low)
	Rivaroxaban 15 mg bid	VTE	New	77	F	62	88	79	256
	Edoxaban 60 mg od	VTE VTE VTE	Chronic New New	79 84 72	M F M	94 76 80	61 61 90	64 (high) 35 28	347 (high) 388 (high) 223
No	Apixaban 2.5 mg bid	AF AF AF	New Chronic New	85 90 73	F M M	62 73 96	23 43 28	99 85 107	121 91 156
	Apixaban 10 mg bid	VTE	New	60	M	88	82	61	286