Skip to main content
. Author manuscript; available in PMC: 2022 Apr 13.
Published in final edited form as: Immunity. 2021 Mar 26;54(4):687–701.e4. doi: 10.1016/j.immuni.2021.03.006

Fig. 3. Molecular requirements for Th1 cell formation during IAV-2W infection.

Fig. 3.

(A) Number of 2W:I-Ab tetramer-binding cells from individual mice (n ≥ three from two independent experiments) of the indicated genotypes on days seven-10 of IAV-2W infection. (B) Flow cytometry plots of 2W:I-Ab tetramer-binding cells from IAV-2W-infected mice of the indicated genotypes. (C-E) Percent T-bet+ (C), mean fluorescence intensity of T-bet+ cells (D), or percent IFN-γ+ cells among T-bet+ 2W:I-Ab tetramer-binding cells two hours after peptide challenge (E) from individual mice (n ≥ three from two independent experiments) of the indicated genotypes. Mean values on scatter plots are indicated with a horizontal bar. Values in A, C-E were compared using one-way ANOVA. ****p < 0.0001; n.s., not significant.