Table 1.

Predictors of treatment-free remission on multivariate analysis in select studies

Study	Factors
DASfree [17]	Older age First-line therapy Longer treatment duration
ENESTop [43]	Longer MR4.5 duration prior to discontinuation
LAST [10••]	Undetectable BCR-ABL RQ-PCR at 3 months after discontinuation Undetectable BCR-ABL1 by digital PCR at time of discontinuation
DESTINY [20•]	Longer treatment duration MR4 group (all BCR-ABL1 measurements after dose reduction < 0.01%)
EURO-SKI [12••]	Longer treatment duration Longer MR4 duration prior to discontinuation
STIM [44]	Low-risk Sokal Longer treatment duration
ISAV [18]	Older age Undetectable BCR-ABL1 by digital PCR at time of discontinuation