Table 2. ANOVA Evaluation of Linear, Quadratic, and Interaction Terms for each Response and Coefficient of Predicted Models.

		DR			ER
source	df	coefficient	sum of squares	p-value	coefficient	sum of squares	p-value
model	14	290.83	1.16 × 105	<0.0001	3.25	119.88	<0.0001
x1	1	–37.45	33660.06	<0.0001	1.1	29.06	<0.0001
x2	1	22.75	12421.5	<0.0001	–0.74	13.04	0.0006
x3	1	2.43	141.14	0.1559	–0.14	0.5	0.4171
x4	1	16.52	6547.21	<0.0001	0.37	3.37	0.0464
x1x2	1	5.12	420.25	0.0206	–0.73	8.45	0.0035
x1x3	1	11.25	2025	<0.0001	0.1	0.16	0.6423
x1x4	1	6.74	726.3	0.0038	–0.51	4.09	0.0302
x2x3	1	–15.11	3654.2	<0.0001	0.17	0.47	0.4339
x2x4	1	–3.15	158.76	0.1338	–0.11	0.18	0.626
x3x4	1	7.87	992.25	0.0012	0.34	1.9	0.1247
x12	1	–15.36	6747.73	<0.0001	0.92	24.29	<0.0001
x22	1	–36.22	37522.32	<0.0001	0.57	9.22	0.0025
x32	1	–1.39	54.96	0.3666	1.1	34.39	<0.0001
x42	1	–26.39	19909.42	<0.0001	0.45	5.77	0.0122
residual	16		1018.35			11.57
lack of fit	10		876.66	0.061		8.85	0.2128
pure error	6		141.69			2.72
total	30		1.17 × 105			131.45