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. 2021 May 27;8(1):G87–G136. doi: 10.1530/ERP-20-0034

Table 3.

Mechanisms and jet direction.

Mechanism of central jets
– Annular dilation and reduced leaflet coaptation through LA enlargement, most often caused by atrial fibrillation. Usually associated with reduced coaptation height and leaflet flattening in systole.
– Central jets are also seen when LV dilation leads to symmetric leaflet tethering and increased coaptation height.
Mechanism of posteriorly directed jets
– Anterior leaflet prolapse and or flail causes simple override of the anterior leaflet directing the regurgitant jet in the opposite direction.
– Ischaemic MR occurs when papillary muscle dysfunction leads to tethering of the posterior leaflet. This inhibits the posterior leaflet from returning to a normal systolic closure position and results in the anterior leaflet coapting with the body of the posterior leaflet rather than the tip. This creates a mechanism of pseudo-prolapse that directs the jet in the direction of the lesion, in this case posteriorly.
– Systolic distortion of the leaflets secondary to the systolic anterior motion of the AMVL.
Anteriorly directed jet
– Posterior leaflet prolapse and or flail causes simple override of the anterior leaflet directing the regurgitant jet in the opposite direction.
Leaflet perforation
– The direction of MR jets due to leaflet perforation depends upon the site of the regurgitant orifice.
– The anterior leaflet base is the most common site of iatrogenic perforation. Assessment post-MV repair should ensure that the CFD box includes the whole annular ring.