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. Author manuscript; available in PMC: 2021 Oct 7.
Published in final edited form as: Nat Protoc. 2017 Mar 9;12(4):732–747. doi: 10.1038/nprot.2017.001

TABLE 1 |.

Troubleshooting table

Step Problem Possible reason Possible solution
4 Breathing is irregular Isoflurane level is too high or low Adjust isoflurane as needed
9 Breathing becomes slow and/or sporadic Potential vagus nerve injury or ligation Check to see whether the vagus nerve was ligated with the carotid artery. If yes, remove sutures and re-tie only the carotid artery
Verify that the vagus nerve is not injured
12 Difficulty inserting tracheal cannula Narrow trachea, large cannula If the cannula is made of plastic, cut the tracheal cannula at an angle for easier insertion
If the cannula is metal, use the end with the rounded edges for insertion
13 Ventilator is not providing flow Tracheal cannula is blocked Disconnect cannula from ventilator and check for blockages, verify air flow, and reconnect
14 Sudden change in CO2 level Temperature Tracheal tube movement—altering of dead space Alter heat-lamp setting or proximity Check tubing—verify tracheal insertion
17 Excess bleeding during laminectomy Ruptured vertebral arteries Use bone wax or hemostatic sponges to minimize blood loss. The hemostatic sponges absorb the blood, quickly clearing the field of view and allowing the investigator to finish the laminectomy
23 Excessive blood loss during craniotomy Vasculature of skull is bleeding Use bone wax to seal the open bone vessels or hemostatic sponges to quickly clear the field of view while finishing the craniotomy
28A(ii) Spinal cord is compressed by the intracellular electrode Various Adjust the shape of the electrode taper
No incoming volley Wrong spinal cord segment Move recording electrode rostrally and caudally along the spinal cord to confirm. Verify the polarity of the stimulating electrodes to rule out anode block
28A(ix) Field potential not visible Incorrect placement of the electrode Move the electrode in the rostro-caudal or mediolateral direction
Change the angle of the electrode with respect to the vertical. The larger the angle, the more lateral the motoneuron pools targeted
28A(x) Intracellular recordings are unstable Movements of the vertebral column Decrease the inspiration volume and adjust the other parameters to maintain adequate ventilation
Improve fixation of the vertebral column on each side of laminectomy to prevent movements