Table 3.
Association Between Brain Region (cc) and Total Daily Activity (min/day), n = 301
| Model 1 | Model 2 | Model 3 | |
|---|---|---|---|
| Beta Coefficient (SE) in units of min/day | |||
| Total brain | 0.38 (0.11)*** | 0.33 (0.13)** | 0.35 (0.13)** |
| Gray matter | 0.50 (0.17)** | 0.30 (0.23) | 0.35 (0.22) |
| White matter | 0.73 (0.20)*** | 0.74 (0.23)** | 0.72 (0.23)** |
| Ventricles | −0.14 (0.27) | 0.06 (0.29) | 0.11 (0.29) |
| Frontal | 0.73 (0.26)** | 0.50 (0.34) | 0.49 (0.33) |
| Gray | 1.03 (0.47)* | 0.30 (0.59) | 0.32 (0.58) |
| White | 1.17 (0.45)* | 1.01 (0.53) | 0.96 (0.53) |
| Parietal | 1.86 (0.52)*** | 1.54 (0.61)* | 1.81 (0.60)** |
| Gray | 2.55 (0.84)** | 1.64 (1.00) | 2.31 (0.99)* |
| White | 2.68 (0.92)** | 2.48 (1.00)* | 2.60 (1.00)** |
| Temporal | 2.14 (0.50)*** | 2.07 (0.59)** | 1.94 (0.59)** |
| Gray | 2.00 (0.81)* | 1.19 (0.93) | 1.11 (0.93) |
| White | 3.88 (0.86)*** | 4.02 (0.94)*** | 3.83 (0.94)*** |
| Occipital | 0.96 (0.60) | 0.33 (0.68) | 0.41 (0.67) |
| Gray | 1.12 (0.92) | −0.26 (1.07) | −0.01 (1.05) |
| White | 2.45 (1.36) | 1.93 (1.43) | 1.86 (1.42) |
| Hippocampus | 8.27 (7.66) | 0.50 (8.68) | 2.40 (8.65) |
| Cerebellum (n = 282) | 1.04 (0.56) | 0.76 (0.60) | 0.80 (0.59) |
Notes: Model 1 adjusted for intracranial volume (cc). Model 2: Model 1 + age (years), sex, race, education (years). Model 3: Model 2 + body mass index (kg/m2), depressive symptoms, usual gait speed (m/s), number of morbid conditions, Apolipoprotein E4 status.
*p < .05, **p < .01, ***p < .001.