Table 2.
Nucleotide sequence variations in the EBER region of 10 samples with OIF, OLP, and OSCC
| Intergenic Region (6796–6955) | EBER-2 (6956–7128) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Oral Lesions | Position | 6808 | 6834 | 6870 | 6884 | 6886 | 6911 | 6927 | 6944 | 6981 | 7085 | 7094 | 7123 |
| EBV-WT (Reference) | T | C | C | G | T | A | G | G | C | C | C | A | |
| AG876 | A | – | – | A | G | G | A | A | – | – | – | G | |
| OIF | MN921213.1 | – | T | T | – | – | – | – | – | – | T | T | – |
| OIF | MN921212.1 | – | T | – | – | – | – | – | – | – | G | – | – |
| OLP | MN921219.1 | – | – | – | – | – | – | – | – | – | – | – | – |
| OLP | MN921220.1 | – | – | – | – | – | – | – | – | T | T | T | – |
| OLP | MN921221.1 | – | T | – | – | – | – | – | – | – | G | – | – |
| OSCC | MN921214.1 | – | T | – | – | – | – | – | – | – | G | – | – |
| OSCC | MN921216.1 | – | – | – | – | – | – | – | – | – | – | – | – |
| OSCC | MN921217.1 | – | –– | – | – | – | – | – | – | – | – | – | – |
| OSCC | MN921218.1 | – | – | – | – | – | – | – | – | – | – | – | – |
| OSCC | MN921215.1 | – | – | – | – | – | – | – | – | – | – | – | – |
Only nucleotides different from EBV-WT are indicated. The changes in coding region of EBER2 and non-coding region between EBER1 and EBER2 are separated by dark line and the positions are shown in the top. The nucleotide positions of identified changes are indicated vertically across the top. The absence of variations is showed with dashes. Previously published sequence of AG876 was taken from Lin et al. [28] and Dolan et al. [54]