Table 5.
Performance of LASSO and comparison models in predicting the critical care outcomes in patients with chest pain
| Accuracy | Sensitivity | Specificity | PPV/Precision | NPV | F1 | Cut-off | AUC | 95%CI | |
|---|---|---|---|---|---|---|---|---|---|
| Training set | |||||||||
| LASSO | 0.861 | 0.847 | 0.881 | 0.853 | 0.867 | 0.845 | 113.0 | 0.924 | 0.896–0.952 |
| HEART | 0.654 | 0.839 | 0.476 | 0.578 | 0.815 | 0.694 | 5.5 | 0.699 | 0.644–0.754 |
| GRACE | 0.707 | 0.588 | 0.805 | 0.714 | 0.703 | 0.645 | 145.5 | 0.737 | 0.684–0.791 |
| TIMI | 0.665 | 0.471 | 0.826 | 0.692 | 0.652 | 0.560 | 5.5 | 0.701 | 0.646–0.756 |
| Testing set | |||||||||
| LASSO | 0.890 | 0.864 | 0.911 | 0.891 | 0.889 | 0.877 | 117.0 | 0.953 | 0.922–0.984 |
| HEART | 0.710 | 0.773 | 0.658 | 0.654 | 0.776 | 0.708 | 6.5 | 0.754 | 0.675–0.832 |
| GRACE | 0.717 | 0.606 | 0.810 | 0.727 | 0.711 | 0.661 | 141.5 | 0.747 | 0.664–0.829 |
| TIMI | 0.683 | 0.500 | 0.835 | 0.717 | 0.667 | 0.589 | 4.5 | 0.735 | 0.655–0.815 |
PPV positive predictive value, NPV negative predictive value, AUC area under the receiver-operating-characteristics curve