Fig. 1. An abbreviated timeline of 19F NMR development with select examples.22–24,27–31,34–38,148 Fluorinated molecules shown in green. Side chains from left to right are: 4-fluorophenylalanine (4FF), 3-fluorotyrosine (3FY), 5-fluorotryptophan (5FW), trifluoromethyl-L-phenylalanine (tfmF), 3FY, 2,2,2-trifluoroethanethiol (TET), and 13C-labeled 3FY.
