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. 2021 Sep 23;27:1609926. doi: 10.3389/pore.2021.1609926

TABLE 2.

General clinical characteristics of different metastatic sites in bone-metastatic LADC patients.

All patients Bone metastasis site
Clavicle or scapula Sternum Skull Humerus Femur Pelvis Rib Spine
Total a 10 10 13 17 22 36 60 103
Age (years)
 <65 6 (60.0%) 7 (70.0%) 5 (38.5%) 13 (76.5%) 16 (72.7%) 21 (58.3%) 36 (60.0%) 58 (56.3%)
 ≥65 4 (40.0%) 3 (30.0%) 8 (61.5%) 4 (23.5%) 6 (27.3%) 15 (41.7%) 24 (40.0%) 45 (43.7%)
Gender
 Male 9 (90.0%) 6 (60.0%) 4 (30.8%) 12 (70.6%) 10 (45.5%) 17 (47.2%) 39 (65.0%) 52 (50.5%)
 Female 1 (10.0%) 4 (40.0%) 9 (69.2%) 5 (29.4%) 12 (54.5%) 19 (52.8%) 21 (35.0%) 51 (49.5%)
Smoking history
 Never smoker 2 (20.0%) 2 (20.0%) 3 (23.1%) 1 (5.9%) 3 (13.6%) 4 (11.1%) 5 (8.3%) 15 (14.6%)
 Ex-smoker 1 (10.0%) 3 (30.0%) 3 (23.1%) 3 (17.6%) 4 (18.2%) 11 (30.6%) 17 (28.3%) 21 (20.4%)
 Current smoker 3 (30.0%) 0 (0.0%) 2 (15.4%) 7 (41.2%) 7 (31.8%) 10 (27.8%) 20 (33.3%) 30 (29.1%)
 N/A 4 (40.0%) 5 (50.0%) 5 (38.5%) 6 (35.3%) 8 (36.4%) 11 (30.6%) 18 (30.0%) 37 (35.9%)
a

The final number of included patients is 209. However, as a single patient does not necessarily present metastasis in specifically one bone, the overall number of metastases might be higher.