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. Author manuscript; available in PMC: 2021 Oct 7.
Published in final edited form as: Curr Probl Pediatr Adolesc Health Care. 2019 Nov 15;49(9):100683. doi: 10.1016/j.cppeds.2019.100683

TABLE 4.

Feminizing effects in transgender females.

Effect Onset Maximum
Redistribution of body fat 3–6 mo 2–3 y
Decrease i n muscle mass and strength 3–6 mo 1–2 y
Softening of skin/decreased oiliness 3–6 mo Unknown
Decreased sexualde5ire 1–3 mo 3–6 mo
Decreased spontaneous erections 1–3 mo 3–6 mo
Male sexual dysfunction Variable Variable
Breast growth 3–6 mo 2–3 y
Decreased testicular volume 3–6 mo 2–3 y
Decreased sperm production Unknown >3 y
Decreased terminal hair growth 6–12 mo >3 ya
Scalp hair Variable b
Voice changes None c

Estimates represent clinical observations: Toorians et al. (149). Asscheman et al. (156). Gooren et al. (157).

a

Complete removal of male sexual hair requires electrolysis or laser treatment or both.

b

Familial scalp hair loss may occur if estrogens are stopped.

c

Treatment by speech pathologists for voice training is most effective.