Table 2.
Linear regression models of the relationship between maximum glucose (mmol/L) on the first day of life and diffusion tensor imaging metrics, including fractional anisotropy (FA) and mean diffusivity (MD). All models are adjusted for postmenstrual age at time of MRI, minimum glucose on first day of life, 5-minute Apgar scores, and umbilical artery pH. Standardized beta coefficients (β) are included. Significant sharpened q-values are marked with an asterisk.
| FA | β | q-value | MD (10−5 mm2/s) | β | q-value | |
|---|---|---|---|---|---|---|
| Anterior white matter | −0.0029 | −0.21 | 0.19 | −1.50 | −0.31 | 0.04* |
| Central white matter | −0.0012 | −0.07 | 0.67 | −0.74 | −0.16 | 0.35 |
| Posterior white matter | −0.0021 | −0.12 | 0.51 | −2.07 | −0.32 | 0.04* |
| Genu of corpus callosum | −0.0074 | −0.19 | 0.25 | −2.30 | −0.27 | 0.08 |
| Splenium of corpus callosum | −0.0021 | −0.07 | 0.66 | −2.33 | −0.43 | 0.001* |
| Caudate | −0.0005 | −0.01 | 1 | −0.90 | −0.22 | 0.19 |
| Lentiform nucleus | 0.000008 | −0.001 | 1 | −0.87 | −0.32 | 0.04* |
| Pulvinar nucleus of thalamus | −0.0018 | −0.11 | 0.51 | −1.21 | −0.38 | 0.001* |
| Ventrolateral nucleus of thalamus | 0.0013 | 0.122 | 0.51 | −0.54 | −0.19 | 0.30 |
| Posterior limb of the internal capsule | −0.0029 | −0.15 | 0.38 | −1.04 | −0.33 | 0.04* |
| Optic radiation | −0.0043 | −0.25 | 0.08 | −2.44 | −0.43 | 0.001* |
| Calcarine cortex | 0.0009 | 0.07 | 0.67 | −0.55 | −0.17 | 0.35 |
| Hippocampus | 0.0009 | 0.05 | 0.74 | −0.47 | −0.09 | 0.59 |