Table 2:

Discrete Feature Values used in the Cumulative Perioperative Model associated with each cumulative step and their univariate ability to predict mortality.

Time step	Feature	Values	C-statistic for 30-day mortality	Cumulative C-statistic for 30-day mortality	C-statistic for 90-day mortality	Cumulative C-statistic for 90-day mortality
1. Procedure Scheduled	Gender	{Female, Male}	0.56	-	0.56	-
	Race	{White, Black, Hispanic, Other}	0.58	-	0.49	-
	Age	numeric	0.58	-	0.60	-
	BMI	6 groups	0.46		0.55
	Charlson Comorbidity Index	Discrete values from 0 – 20, inclusive	0.69		0.69
Best step 1 features	Race + CCI			0.70	Gender + CCI	0.71
2. Morning of surgery	Start location	{Home, Ward, ICU, EC}	0.61		0.61
	Emergency status	{Absent, Present}	0.58		0.57
	ASA classification	Numeric: {1,2,3,4,5}	0.65		0.62
	Best step 1 & all step 2 features			0.76		0.78
3. Procedures complete	Adrenalectomy	{Absent, Present}	0.49	Excluded	0.49	Excluded
	Colectomy	{Absent, Present}	0.48	Excluded	0.52
	Cystectomy	{Absent, Present}	0.54		0.53
	Enterectomy	{Absent, Present}	0.57		0.55
	Enteroenterosto my	{Absent, Present}	0.51		0.52
	Enterostomy	{Absent, Present}	0.53		0.53
	Gastrectomy	{Absent, Present}	0.50	Excluded	0.49	Excluded
	Hepatectomy	{Absent, Present}	0.48	Excluded	0.52
	Hysterectomy	{Absent, Present}	0.57		0.57
	Jejunostomy	{Absent, Present}	0.51		0.51
	Nephrectomy	{Absent, Present}	0.48	Excluded	0.51
	Oophorectomy	{Absent, Present}	0.50	Excluded	0.51
	Pancreatectomy	{Absent, Present}	0.52		0.51
	Pelvic exenteration	{Absent, Present}	0.51		0.51
	Splenectomy	{Absent, Present}	0.50	Excluded	0.50	Excluded
	Best step 1, all step 2, & discriminative step 3 features			0.79		0.78
4. Anesthesia complete	Surgical Apgar score	{≤5, 6, 7, 8, 9, 10}	0.76	0.84	0.70	0.82
5. Post PACU	Extended PACU	{Absent, Present}	0.52	Excluded	0.52	Excluded
	Surgical destination	{Discharge, Ward, ICU, Surgery}	0.72	0.86	0.63	0.82
6. Six days post-operative	Delayed ICU admit	{Home, Home Care, Institutional Care, PACU, Hospital Ward, ICU}	0.56	0.87	0.53	0.84