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Noncompartmental Analysis of Dopaminergic Derivative Concentrations in the Whole Rat Eye, Retina/Vitreous, and Blood After a Single Topical Treatment of Etilevodopa 10% In Vivo
| Group | AUC0→∞ (ng/mL) | T1/2 (h) | Mean Resident Time (h) | R 2 |
|---|---|---|---|---|
| Whole eye | 4298.5 | 1.4 | 1.4 | 0.95 |
| Retina/Vitreous | 817.5 | 8.0 | 11.7 | 0.56 |
| Blood | 11.2 | 3.4 | 4.6 | 0.95 |
AUC, area under the curve; T1/2, half-life.
