Table 6.

Overview of GRS-MAP associations.

GRS	MAP test	No. SNPs in optimal GRS	R2	Coefficient; SE	Empirical p-valuea
CD	IgA—MAP0210c	23 117	0.79%	-144; 84	0.52
	IgA—MAP2609	69 507	1.10%	-258; 112	0.20
	IgM—MAP0210c	343 804	0.46%	-427; 276	0.66
	IgM—MAP2609	317	0.60%	-10; 6	0.56
UC	IgA—MAP0210c	34 068	1.09%	248; 122	0.38
	IgA—MAP2609	4 551	0.46%	42; 28	0.80
	IgM—MAP0210c	3 638	1.14%	-57; 23	0.23
	IgM—MAP2609	2 788	0.52%	-51; 33	0.68

SNP, single nucleotide polymorphism; GRS, genetic risk score; SE, standard error; CD, Crohn’s disease; UC, ulcerative colitis.

^aEmpirical p-value refers to p-value after 10 000 rounds of permutation.