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. 2021 Sep 27;17(9):e1009820. doi: 10.1371/journal.pgen.1009820

Table 2. General properties of HC20_373 and other HC20 clusters.

Pairwise SNP Differences
HC20 cluster Tree Number No. genomes Serovar Geography Predominant Host Dates Mean Median Max
Random large HC20 clusters
10 45443 315 Adelaide U.S.A. Swine (83%) 2009–2020 21.5 16.0 69.0
44 45449 970 Newport U.S.A. Cows (61%); Humans (23%) 2000–2020 19.9 20.0 54.0
122 45447 1156 Newport U.S.A. Human (55%); Environment (41%) 1998–2020 25.0 23.0 65.0
125 45450 576 Bertha U.S.A. Chickens (51%); Humans (29%) 1994–2020 27.9 27.0 73.0
557 45446 849 Muenchen U.S.A. Chickens (79%); Swine (7%) 1988–2020 19.4 13.0 71.0
710 45445 420 Johannesburg U.S.A. Swine (82%) 2003–2020 17.3 12.0 59.0
1348 45423 844 Enteritidis PT8 UK Human (95%); Feeder Mice1 1972–2020 9.5 7.0 59.0
1487 45424 359 Typhimurium England Human (97%) 2006–2020 19.7 15.0 57.0
Outbreaks
4179 60146 581 Newport North America Human (97%) 2010–2021 3.2 1.0 56.0
39803 45421 222 Hadar U.S.A. Human (95%) 2000–2018 3.0 3.0 17.0
Lab strains
373 60131 496 ATCC14028s global Laboratory and Nature 2000–2020 1.9 1.0 15.0
5519 60183 46 SL1344 Europe Laboratory (89%) 2002–2018 4.6 5 32
20633 60214 50 NCTC 7832 UK, Ireland Laboratory? 2006–2021 2.6 2 11

NOTE: Tree number: Tree ID in EnteroBase of Ninja NJ trees of each cluster.

1Information from Marie Chattaway, PHE, UK has confirmed that HC20_1348 corresponds to the cluster of Enteritidis PT8 isolates that contaminated frozen feeder mice for pet reptiles [27,63].