Table 4. Statistically significant temporal signals within non-repetitive core genome SNPs in HC20_373 and other HC20 clusters.
Marginal likelihood | Log Bayes Factor | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
HC20 cluster | No. genomes | Serovar | Dates | Contemp Strict | Contemp Relaxed | Strict | Relaxed | BF1 | BF2 | BF3 |
10 | 256 | Adelaide | 2009–2020 | -6300296 | -6300266 | -6300028 | -6300027 | 268 | 239 | 1 |
44 | 807 | Newport | 2000–2020 | -6741201 | -6741075 | -6740307 | -6740164 | 894 | 911 | 143 |
122 | 805 | Newport | 1998–2020 | -6942726 | -6942748 | -6942657 | -6942593 | 69 | 155 | 64 |
125 | 445 | Bertha | 1994–2020 | -6788539 | -6788497 | -6788366 | -6788190 | 173 | 307 | 176 |
557 | 749 | Muenchen | 1988–2020 | -6721331 | -6721275 | -6720904 | -6720738 | 427 | 537 | 166 |
710 | 405 | Johannesburg | 2003–2020 | -6169794 | -6169764 | -6169324 | -6169329 | 470 | 435 | -4 |
1348 | 781 | Enteritidis PT8 | 1972–2020 | -6845700 | -6845709 | -6845096 | -6844990 | 604 | 719 | 106 |
1487 | 341 | Typhimurium | 2006–2020 | -6787811 | -6787819 | -6787671 | -6787677 | 140 | 142 | -6 |
4179 | 377 | Newport | 2010–2021 | -6680482 | -6680478 | -6680401 | -6680406 | 82 | 72 | -6 |
373 | 419 | ATCC14028s | 2000–2020 | -6706284 | -6706329 | -6706189 | -6706166 | 95 | 163 | 23 |
20633 | 44 | NCTC 7832 | 2006–2021 | -6375734 | -6375742 | -6375728 | -6375732 | 6 | 10 | -4 |
NOTE: Data are as in Table 2, except that the HC20_5519 and HC20_39803 were excluded because they did not possess statistically significant evidence for temporal signals. Furthermore, only genomes were included with metadata for calendar year or isolation and which were not outliers in an analysis with TempEst [38].
Marginal likelihoods are abbreviated as Contemp Strict: strict clock with isochronous dates; Contemp Relaxed: relaxed clock with isochronous dates; Strict: strict molecular clock with heterochronous dates; Relaxed: relaxed molecular clock with heterochronous dates.
BF1 (Log Bayes Factor 1) is Strict vs Contemp Strict. BF2 is Relaxed vs Contemp Relaxed. BF3 is Relaxed vs Strict.