Fig 6. 80% of the consistently co-DE pairs are involved in STRINGdb interaction, belong to the same GO or are located on the same TAD.

a) DS co-DE network (as in Fig 4) where only the consistent co-DE edges with a STRINGdb interaction are reported b) Barplot representing the number of TADs per human chromosome. TADs containing at least one of the top-500 genes are in dark gray c) Boxplot showing the number of consistently DE genes per TADs per each chromosome d) Heatmap showing the 1243 edges consistently co-DE gene pairs that are in the same TAD, in the same Gene Ontology or involved in a STRINGdb interaction.