Table 3.
Hazard Ratios (95% Confidence Intervals) and R2 (95% Confidence Intervals) Calculated for Logistic Regression Models Estimating Schizophrenia Risk Associated With NDVI During Childhood and Polygenic Risk Score Singly or Jointly Along With Age, Gender, Birth Year, Parental History of Mental Disorder, and Parental Socioeconomic Status (and First 10 Genomic Principal Components) (n = 19 746)
| OR (95% CI) | Nagelkerke’s R2 (%) | R 2 on Liability Scale (%) | |
|---|---|---|---|
| Model 1 | 2.21 (1.63–2.90) | 1.45 (1.07–1.90) | |
| Childhood NDVI | 0.13 (0.10–0.18) | ||
| Model 2 | 1.54 (1.17–2.24) | 1.01 (0.77–1.46) | |
| Polygenic risk score for schizophrenia | 1.32 (1.25–1.38) | ||
| Model 3 | 3.65 (3.02–4.63) | 2.40 (1.99–3.07) | |
| Childhood NDVI | 0.14 (0.10–0.19) | ||
| Polygenic risk score for schizophrenia | 1.32 (1.25–1.38) | ||
| Model 4 | 3.65 (3.03–4.65) | 2.41 (2.00–3.08) | |
| Childhood NDVI | 0.13 (0.10–0.18) | ||
| Polygenic risk score for schizophrenia | 1.29 (1.19–1.39) | ||
| Interaction term | 1.10 (0.84–1.43) |
Note: CI, confidence interval; OR, odds ratio; NDVI, normalized difference vegetation index.