Table 3.
Plasma fatty acid status in hemodialysis patients.
| Fatty acid | All patients | Adequate Zn intake | Inadequate Zn intake |
|---|---|---|---|
| % | n = 18 | n = 22 | |
| 16:0 | 28.60 ± 1.94 | 28.44 ± 2.03 | 28.31 ± 2.28 |
| 18:0 | 19.06 (17.68–19.81) | 17.80 (17.04–19.70–24.82) | 19.36 (18.36–20.29) |
| SFA | 47.52 ± 2.32 | 46.85 ± 2.22 | 47.96 ± 2.30 |
| 16:1n−7 | 0.38 (0.26–0.46) | 0.36 (0.22–0.45) | 0.40 (0.27–0.48) |
| 18.1n-9 | 9.61 (8.54–10.25) | 9.73 (8.38–10.19) | 9.87 (8.86–10.44) |
| 18:1n−7 | 1.85 (1.70–2.09) | 1.73 (1.66–2.02) | 1.95 (1.74–2.08) |
| MUFA | 11.84 (11.03–12.68) | 11.81 (10.72–12.20) | 12.31 (11.22–12.87) |
| 18:2n-6 (LA) | 21.89 ± 3.14 | 22.22 ± 2.93 | 21.64 ± 3.99 |
| 20:3n-6 (DGLA) | 2.87 ± 0.66 | 3.02 ± 0.74 | 2.94 ± 0.63 |
| 20:4n-6 (AA) | 11.78 ± 2.25 | 12.14 ± 2.06 | 11.61 ± 2.62 |
| 22:4n-6 | 0.66 (0.50–0.90) | 0.67 (0.46–1.01) | 0.60 (0.45–0.71) |
| n-6 | 37.27 ± 3.03 | 38.12 ± 2.69 | 36.79 ± 7.48 |
| 18:3n-3 | 0.11 (0.08–0.16) | 0.12 (0.08–0.15) | 0.09 (0.07–0.19) |
| 20:5n−3 (EPA) | 0.22 (0.16–0.31) | 0.24 (0.14–0.32) | 0.18 (0.16–0.32) |
| 22:5n-3(DPAn-3) | 0.56 (0.48–0.69) | 0.62 (0.48–0.80) | 0.54 (0.44–0.59) |
| 22:6n-3 (DHA) | 2.26 ± 0.57 | 2.36 ± 0.62 | 2.08 ± 0.41 |
| n-3 | 3.25 ± 0.74 | 3.42 ± 0.83 | 2.97 ± 0.51* |
| n-6/n-3 | 11.99 ± 2.54 | 11.71 ± 2.66 | 12.68 ± 2.20 |
| EPA+DHA | 2.51 ± 0.60 | 2.61 ± 0.63 | 2.29 ± 0.42 |
| PUFA | 40.52 ± 3.31 | 41.54 ± 2.71 | 39.77 ± 3.61 |
| D5D | 4.28 ± 1.15 | 4.20 ± 1.09 | 4.06 ± 1.11 |
| D6D | 0.128 (0.106–0.153) | 0.129 (0.109–0.149) | 0.127 (0.102–0.185) |
| SCD16 | 0.013 (0.009–0.016) | 0.012 (0.008–0.016) | 0.014 (0.010–0.016) |
| SCD18 | 0.49 (0.43–0.57) | 0.53 (0.45–0.57) | 0.49 (0.44–0.57) |
| LA/DGLA | 8.10 ± 2.53 | 7.80 ± 2.17 | 7.79 ± 2.72 |
| ELO | 2.47 (0.96–11.0) | 3.29 (3.10–11.00) | 2.51 (1.00–5.17) |
Continuous variables are shown as means ± standard deviation for a normal distribution or medians (interquartile range) for a non-normal distribution; SFA, saturated fatty acids; MUFA, monounsaturated fatty acids; LA, linoleic acid; DGLA, dihomo-γ-linolenic acid; AA, arachidonic acid; EPA, eicosapentaenoic acid; DPA, docosapentaenoic acid; DHA, docosahexaenoic acid; PUFA, polyunsaturated fatty acids; D5D, Δ-5-desaturase; AA/DGLA (20:4 n-6/20:3 n-6), D6D, Δ-6-desaturase: DGLA/LA (20:3 n-6/18:2 n-6); SCD16 and 18, stearoil-CoA desaturase 16 and 18, ELO, elongase: (DPAn-3/EPA),
*
p < 0.05 inadequate Zn intake vs. adequate Zn intake.