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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Nanoscale Horiz. 2021 Jul 20;6(9):696–717. doi: 10.1039/d1nh00179e

Figure 7.

Figure 7.

IONP-based cancer vaccine as a predictive biomarker for cancer treatment. (a) DCs incubated with IONPs complexed with RNA were tracked using MRI, as shown in the difference in signal intensity in each lymph node. (b) Comparison between iron content in the lymph node and T2 MRI signal shows that IONPs can be used to quantitatively track DC migration. (c) Correlation between tumor size 17 days after treatment and MRI intensity in the lymph node at day 2. (d) Kaplan-Meier survival curves for all treated mice, divided into groups that responded to vaccine treatment depending on MRI intensity in the lymph node at day 2. Reproduced with permission.18 Copyright 2019, American Chemical Society.