Figure 3. Haploid natural isolates exhibit a 10-fold range of mutation rate variation.

Mutation rate variation measured among haploid natural isolates using our CAN1 reporter gene Luria-Delbrück fluctuation assays. Strains are shown ordered by their mean mutation rates. Mutation rates for each strain were estimated using at least two replicates, each estimate represented here by a dot. A standard boxplot spans the interquartile confidence interval of possible mutation rates for each strain.

Figure 3—figure supplement 1. Relationship between growth rate versus measured mean mutation rate.

Peter et al., 2018 measured growth rates from colony size from each of the 1011 yeast genomes. As shown, we see no evidence of a relationship between these variables for the strains included in our fluctuation study.