Table 13.

Selected biological processes (KEGG) with changes in ipsilateral dorsal root ganglion (L4-L5) 7 days after SNI. Comparisons are All SNI vs. All Sham (n = 14), Male SNI vs. male Sham (n = 7) and Female SNI vs. female Sham (n = 7). Analysis conducted with Advaita iPathwayguides biological processes tool, Elim pruning (EP) used for multiple comparisons correction, with cut-off value < 0.05. Not significant = EP > 0.05

Biological processes in dorsal root ganglia
Biological process	Male EP	Female EP
regulation of sensory perception of pain	0.023	0.022
positive regulation of T-helper cell differentiation	NS	0.0014
T cell activation involved in immune response	0.027	0.021
T cell mediated immunity	NS	0.037
T cell migration	NS	0.039
T cell apoptotic process	0.031	NS
T cell chemotaxis	0.030	NS
regulation of alpha-beta T cell differentiation	NS	0.021
regulation of T helper 1-type immune response	NS	0.003
positive regulation of T helper 1 cell cytokine production	0.017	0.008
T helper 1 cell differentiation	NS	0.008
positive regulation of T helper 2 cell cytokine production	0.047	0.020
regulation of T helper 2 cell differentiation	NS	0.031
positive regulation of T helper 2 cell differentiation	0.017	NS
T helper 2 cell differentiation	0.047	NS
T helper 17 cell differentiation	NS	0.031
positive regulation of T helper 17-type immune response	0.047	0.020
B cell receptor signalling pathway	NS	1.400e-4
negative regulation of B cell proliferation	NS	0.001
positive regulation of B cell proliferation	0.004	4.100e-4
negative regulation of B cell receptor signalling pathway	NS	0.008
regulation of B cell receptor signalling pathway	0.011	0.007
regulation of microglial cell migration	NS	0.020
microglial cell activation	NS	0.002
neuronal action potential	NS	0.022
regulation of neuronal synaptic plasticity	0.036	NS
positive regulation of synaptic transmission, glutamatergic	0.006	0.040
regulation of synaptic transmission, GABAergic	0.016	NS