Fig. 1.

In glioma tissues and GBM cell lines, NEAT1 was upregulated whereas miR-128-3p showed an obvious decrease, and miR-128-3p was localized in both the nucleus and cytoplasm. a, b qRT-PCR showing NEAT1 and miR-128-3p expression levels in normal brain tissues (NBT) and different grades of glioma tissues (LGG, HGG), each group had 10 samples. *p < 0.05, **p < 0.01, ***p < 0.001. c, d Expression of NEAT1 and miR-128-3p in normal human astrocytes (HA) and GBM cell lines (U87MG, U118MG, A172, U251MG). *p < 0.05, **p < 0.01, ***p < 0.001 VS HA. e FISH assay verified the subcellular localization of miR-128-3p