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. 2021 Jun 30;8(5):4055–4066. doi: 10.1002/ehf2.13488

Table 3.

Abnormal PTFV1 is an independent predictor for CaMKII activity

n = 20

 

Univariate linear regression analysis

Multivariate linear regression analysis

Adj. r 2 = 0.255; P = 0.032

CaMKII activity (normalized to CaMKII expression) B (95% CI) P‐value B (95% CI) P‐value
Abnormal PTFV1 (≥4000 ms*μV) 0.591 (0.106; 1.077) 0.020 0.542 (0.057; 1.027) 0.031
Age (years) −0.022 (−0.053; 0.008) 0.143 −0.017 (−0.045; 0.011) 0.210
Male 0.032 (−0.620; 0.683) 0.920
Body mass index (kg/m2) 0.012 (−0.058; 0.082) 0.729
Paroxysmal atrial fibrillation 0.205 (−0.579; 0.988) 0.590
Existing heart failure 0.035 (−0.540; 0.611) 0.899
eGFR (mL/min/1.73 m2) −0.001 (−0.012; 0.009) 0.781

CaMKII, Ca/calmodulin‐dependent protein kinase II; CI, confidence interval; eGFR, estimated glomerular filtration rate; PTFV1, P‐wave terminal force in lead V1.

Linear regression analyses between an abnormal PTFV1 and CaMKII activity in right atrial appendage biopsies of patients undergoing coronary artery bypass grafting. Bold font is used to highlight statistically significant P‐values < 0.05.