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. 2021 Jul 9;8(5):3769–3782. doi: 10.1002/ehf2.13445

Table 5.

C‐statistics of adjusted models without or with biomarkers

CRP Fibrinogen IL‐6
Event Models Female Male Female Male Female Male
HF Without biomarker 0.818 (0.027) 0.82 (0.023) 0.823 (0.026) 0.82 (0.023) 0.834 (0.027) 0.823 (0.024)
With categorized biomarker 0.824 (0.028) 0.821 (0.024) 0.822 (0.026) 0.831 (0.022) 0.848 (0.023) 0.828 (0.024)
With recent measure only 0.829 (0.026) 0.825 (0.024) 0.826 (0.025) 0.647 (0.038) 0.833 (0.026) 0.835 (0.023)
With annual change and baseline level 0.825 (0.027) 0.824 (0.023) 0.825 (0.026) 0.625 (0.037) 0.863 (0.027) 0.832 (0.023)
CVD Without biomarker 0.728 (0.023) 0.708 (0.018) 0.729 (0.023) 0.704 (0.018) 0.721 (0.025) 0.717 (0.018)
With categorized biomarker 0.727 (0.023) 0.715 (0.018) 0.736 (0.021) 0.706 (0.018) 0.723 (0.025) 0.717 (0.018)
With recent measure only 0.728 (0.023) 0.717 (0.017) 0.729 (0.023) 0.712 (0.018) 0.723 (0.025) 0.717 (0.018)
With annual change and baseline level 0.728 (0.023) 0.715 (0.017) 0.733 (0.022) 0.711 (0.017) 0.722 (0.025) 0.713 (0.018)
Death Without biomarker 0.768 (0.018) 0.766 (0.015) 0.765 (0.018) 0.768 (0.015) 0.765 (0.02) 0.768 (0.016)
With categorized biomarker 0.769 (0.018) 0.766 (0.015) 0.764 (0.018) 0.77 (0.015) 0.77 (0.02) 0.783 (0.015)
With recent measure only 0.768 (0.018) 0.768 (0.015) 0.764 (0.018) 0.772 (0.015) 0.765 (0.02) 0.79 (0.015)
With annual change and baseline level 0.771 (0.018) 0.768 (0.015) 0.769 (0.018) 0.771 (0.015) 0.766 (0.02) 0.788 (0.015)

Standard errors are in parentheses. Bold numbers belong to the models with significant association between event and biomarker.