Table 3.

Binding affinity for compounds 8–12 (IC₅₀ values in μM).^[a]

	R (N)	R (−1)	CBX1	CBX6	CBX7	CBX8
8			> 500	3.2	> 500	18
9			> 300	9.8[b]	23[b][c]	2.7
10			> 300	72	162	68
11			> 300	12	105	6.5
12			> 500	17	>300	6.2

^[a]Competitive FP assays performed in triplicate unless stated otherwise. Raw data and asymmetric 95% confidence intervals are reported in SI.

^[b]Competitive FP assays performed in duplicate

^[c]Poor fit. See SI.