Table 4.

Binding affinity for compounds 10, 11 and 13–19 (IC₅₀ values in μM).^[a]

	R (N)	R (−3)	CBX1	CBX6	CBX7	CBX8
10			> 300	72	162	68
13			> 300	32	104	25
11			> 300	12	105	6.5
14			> 300	8.3	171	5.8
15			> 500	12	>250	0.6[b]
16			N.T.[c]	9.3	>500	1.8
17			N.T.[c]	68	>500	20
18			> 500	33	>250	17
19			N.T.[c]	5.0	209	1.6

^[a]Competitive FP assays performed in triplicate unless stated otherwise. Raw data and asymmetric 95% confidence intervals are reported in SI.

^[b]Estimated value because IC₅₀ is outside of linear range of assay.^[22–23]

^[c]Not tested