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. Author manuscript; available in PMC: 2021 Nov 27.
Published in final edited form as: Nat Biomed Eng. 2021 May 27;5(9):1048–1058. doi: 10.1038/s41551-021-00728-7

Table 1.

IC50 (in μM) values of TMZ, OxaPt(IV) and 56MESS in different cell lines.

Drug/Cell line LN229-TS LN229-TR U87 PDX
TMZ 2.0 162.6 39.9 189.6
OxaPt(IV) 0.7 (2.9) 0.6 (271) 0.2 (199.5) 0.3 (632)
56MESS 1.1 (1.8) 0.5 (325.2) 1.1 (36.3) 1.7 (111.5)
NP-OxaPt(IV) 1.0 (2.0) 0.2 (813) 0.1 (399) 0.2 (948)
NP-56MESS 0.6 (3.3) 0.2 (813) 0.7 (57) 0.7 (270.9)

The numbers within parentheses represent the radios of the IC50 values of TMZ to those of each drug.