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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Eur J Haematol. 2021 Aug 6;107(5):503–516. doi: 10.1111/ejh.13687

TABLE 1.

Incidence of lymphoma in common variable immunodeficiency (CVID)

Studied group CVID cohort number Publication year Diagnosed lymphoma (%) Comments
United Kingdom57 220 1985 1.4% 3 NHL**
Sweden and Denmark21 176 2002 2.3% 4 NHL
Italy58 224 2007 1.8% 4 NHL
ESID+12 334 2008 0.9% 3 NHL
Mount Sinai11 473 2012 8.2% 39 NHL
ESID+22 902 2014 2.5% 25 NHL
Prague23 295 2018 3.7% 4 NHL; 5 HD; 2 T-cell lymphoma
ESID+14 972 2018 3.8% Lymphomas not otherwise specified
Italy24 455 2018 8.4% 33 NHL; 5 HD
USIDNET*20 1,285 2018 2.9% 37 NHL
Duke University26 198 (91 pediatric-onset; 107 adult-onset) 2019 9.1% 18 NHL/leukemia

Note:

+

ESID: European Society for Immunodeficiencies; HD: Hodgkin lymphoma.

*

USIDNET: United States Immunodeficiency Network.

**

NHL: non-Hodgkin lymphoma.