Table 3.
Hazard ratios (HR) for cardiovascular disease (CVD) events, CVD mortality and total mortality according to Hb quartiles.
| CVD events | CVD mortality | Total Mortality | |
|---|---|---|---|
| HR (95% CI) | HR (95% CI) | HR (95% CI) | |
| Hb (g/L) | |||
| Hb quartile 1 (Low) | 1 | 1 | 1 |
| Hb quartile 2 | 1.43 (0.99; 2.06) | 1.63 (0.76; 3.51) | 1.03 (0.69; 1.54) |
| Hb quartile 3 | 0.96 (0.65; 1.42) | 1.62 (0.76; 3.46) | 1.02 (0.68; 1.53) |
| Hb quartile 4 (High) | 1.25 (0.85; 1.82) | 2.08 (1.01; 4.29) | 1.48 (1.01; 2.16) |
| Age (years) | 1.06 (1.04; 1.09) | 1.07 (1.02; 1.12) | 1.09 (1.06; 1.11) |
| Sex (male) | 1.88 (1.33; 2.68) | 2.16 (1.12; 4.17) | 1.45 (1.01; 2.08) |
| Smoking (pack-years) | 1.013 (1.004; 1.021) | 1.029 (1.015; 1.042) | 1.022 (1.013; 1.030) |
| Alcohol consumption (g/week) | 1.000 (0.999; 1.002) | 1.002 (1.000; 1.004) | 1.002 (1.000; 1.003) |
| BMI (kg/m2) | 1.00 (0.96; 1.03) | 1.02 (0.97; 1.08) | 1.00 (0.98; 1.04) |
| Systolic blood pressure (mmHg) | 1.00 (0.99; 1.02) | 1.02 (1.00; 1.03) | 1.00 (0.99; 1.01) |
| Diastolic blood pressure (mmHg) | 0.99 (0.97; 1.00) | 0.98 (0.95; 1.01) | 1.00 (0.98; 1.02) |
| Blood pressure medication | 1.80 (1.34; 2.41) | 1.56 (0.91; 2.67) | 1.22 (0.91; 1.63) |
| HDL cholesterol (mmol/L) | 0.60 (0.37; 0.97) | 1.37 (0.61; 3.06) | 1.12 (0.74; 1.73) |
| LDL cholesterol (mmol/L) | 1.17 (1.01; 1.36) | 1.10 (0.84; 1.45) | 0.95 (0.81; 1.10) |
| Lipid medication | 1.09 (0.56; 2.10) | 1.96 (0.75; 5.14) | 1.49 (0.78; 2.87) |
Cox regression models representing HR with 95% confidence intervals (CIs) for CVD events (n = 231, 23.8%), CVD-related mortality (n = 70, 7.2%) and total mortality (n = 213, 22%). The regression models include variables as reported in the table. Hb quartile 1 = reference group.