Table 1.
A comparison of the amino acids in the urine and serum in the control group and septic patients.
| Variable | Urine | Serum | ||||
|---|---|---|---|---|---|---|
| Control (n = 15) | Septic patients (n = 15) | p | Control (n = 15) | Septic patients (n = 15) | p | |
| Aminoadipic acid (AAA) | {29.60; 31.70; 58.25} | {23.65; 25.70; 29.25} | 0.0007 | {27.21; 29.09; 31.38} | {22.55; 22.80; 26.15} | 0.0164 |
| Arginine (Arg) | {17.70; 20.40; 31.15} | {22.60; 29.55; 61.10} | 0.0145 | {29.10; 88.10; 105.35} | {124.85; 200.45; 230.20} | < 0.0001 |
| a-Aminoisobutyric acid (ABA) | {21.25; 27.55; 71.05} | {23.35; 46.65; 116.20} | 0.1607 | {21.24; 21.63; 22.51} | {22.60; 24.55; 36.10} | 0.0001 |
| Glycine (Gly) | {111.80; 123.80; 143.95} | {200.40; 254.65; 355.65} | < 0.0001 | {154.75; 601.00; 709.95} | {733.55; 1192.25; 1438.80} | 0.0004 |
| Histidine (His) | {185.50; 236.25; 358.15} | {41.05; 73.60; 367.25} | 0.0295 | {27.35; 124.65; 152.65} | {151.20; 217.60; 315.45} | 0.0007 |
| 4-Hydroxyproline (hPro) | {12.99; 13.20; 18.83} | {13.68; 17.64; 18.31} | 0.2328 | {16.89; 18.99; 33.19} | {33.61; 53.29; 96.99} | < 0.0001 |
| Leucine (Leu) | {24.70; 26.15; 31.00} | {24.85; 29.32; 43.90} | 0.3245 | {53.35; 110.80; 152.55} | {151.75; 241.55; 325.95} | 0.0001 |
| Isoleucine (Ile) | {22.40; 23.80; 33.65} | {21.26; 23.98; 48.77} | 1.0000 | {36.95; 66.05; 89.35} | {114.65; 160.55; 240.70} | < 0.0001 |
| Lysine (Lys) | {44.65; 56.35; 85.85} | {30.60; 45.10; 155.55} | 0.3892 | {95.00; 217.75; 256.35} | {269.50; 362.60; 486.10} | 0.0003 |
| 3-Methyl-histidine (mHis) | {117.10; 225.15; 559.50} | {39.20; 59.10; 89.85} | 0.0001 | {18.80; 20.20; 23.45} | {26.05; 30.15; 44.40} | 0.0010 |
| Ornithine (Orn) | {25.80; 28.15; 34.40} | {26.00; 35.75; 58.10} | 0.1873 | {39.50; 87.60; 113.35} | {118.05; 184.75; 247.85} | 0.0007 |
| Phenylalanine (Phe) | {32.15; 35.35; 49.70} | {27.45; 35.15; 72.10} | 0.7130 | {37.90; 84.85; 103.95} | {160.10; 228.05; 266.60} | < 0.0001 |
| Sarcosine (Sarc) | {82.49; 142.18; 241.64} | {53.74; 130.45; 314.69} | 0.5949 | {229.91; 544.65; 759.26} | {579.10; 855.15; 1189.31} | 0.0128 |
| Serine (Ser) | {148.35; 177.10; 209.50} | {60.95; 135.55; 259.30} | 0.2671 | {60.20; 174.15; 219.60} | {143.25; 205.20; 336.05} | 0.0555 |
| Threonine (Thr) | {42.55; 49.10; 79.90} | {37.30; 48.40; 173.95} | 1.0000 | {64.35; 178.40; 207.95} | {157.40; 274.75; 392.80} | 0.0145 |
| Tyrosine (Tyr) | {44.15; 53.45; 62.90} | {30.30; 36.10; 78.75} | 0.1160 | {49.70; 85.50; 99.05} | {130.85; 146.05; 212.70} | < 0.0001 |
| Citruline (Cit) | {19.05; 19.40; 20.05} | {19.50; 19.95; 31.85} | 0.0295 | {23.45; 33.00; 42.10} | {28.75; 37.15; 48.70} | 0.2671 |
| Asparagine (Asn) | {26.25; 29.10; 43.70} | {23.95; 28.30; 45.70} | 0.5125 | {23.25; 31.00; 33.10} | {45.85; 54.53; 63.15} | < 0.0001 |
| Glutamine (Gln) | {67.55; 77.50; 107.90} | {44.60; 57.25; 112.25} | 0.2671 | {76.90; 199.65; 237.40} | {219.80; 365.95; 444.65} | 0.0007 |
| Tryptophan (Trp) | {13.55; 14.10; 16.10} | {11.90; 13.35; 17.00} | 0.1607 | {14.70; 19.90; 22.15} | {15.70; 19.55; 21.85} | 1.0000 |
| Aminopimelic acid (APA) | {38.97; 38.98; 39.01} | {38.35; 38.38; 38.41} | < 0.0001 | {19.60; 19.60; 19.70} | {19.60; 19.70; 19.70} | 0.0408 |
| Glycine-proline (dipeptide) (Gly-Pro) | {38.07; 38.57; 40.25} | {37.76; 38.61; 39.55} | 1.0000 | {36.87; 36.98; 37.06} | {19.10; 19.15; 19.30} | < 0.0001 |
| Thioproline (tPro) | {37.70; 37.75; 37.82} | {37.60; 37.61; 37.65} | 0.0001 | {37.59; 37.59; 37.65} | {19.95; 20.00; 20.10} | < 0.0001 |
Data is presented as {1st quartile; median value; 3rd quartile}; cases in which p < 0.05 (U Mann–Whitney test) are marked in bold. The median value is expressed as µmol/L.