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. 2021 Oct 7;11:19977. doi: 10.1038/s41598-021-99482-8

Table 3.

A comparison of the amino acids in the urine and serum in survivors and non-survivors.

Variable Urine Serum
Survivors (n = 11) Non-survivors (n = 4) p Survivors (n = 11) Non-survivors (n = 4) p
Aminoadipic acid (AAA) {23.95; 25.70; 27.90} {23.43; 26.78; 250.35} 0.7531 {22.55; 22.70; 23.55} {23.45; 25.85; 31.13} 0.4894
Arginine (Arg) {20.30; 28.65; 34.40} {30.03; 48.23; 359.28} 0.1377 {124.85; 200.45; 230.20} {122.63; 203.00; 263.20} 0.9495
a-Aminoisobutyric acid (ABA) {22.75; 46.65; 116.20} {25.78; 54.08; 577.30} 0.5714 {22.60; 24.00; 31.90} {23.88; 30.83; 42.53} 0.6608
Glycine (Gly) {190.05; 231.10; 309.05} {241.15; 435.08; 1944.70} 0.2256 {780.00; 1192.25; 1438.80} {356.45; 969.73; 1418.33} 0.4894
Histidine (His) {37.80; 68.45; 265.05} {71.93; 275.43; 459.43} 0.2256 {151.20; 183.35; 298.20} {147.95; 288.65; 364.88} 0.5714
4-Hydroxyproline (hPro) {13.16; 15.32; 18.31} {15.74; 17.84; 19.30} 0.4894 {32.25; 39.12; 56.37} {92.25; 133.06; 167.73} 0.0029
Leucine (Leu) {24.65; 28.70; 35.25} {27.08; 104.31; 1115.85} 0.3429 {149.50; 198.25; 368.40} {242.63; 280.60; 321.73} 0.3429
Isoleucine (Ile) {21.26; 23.01; 31.82} {34.51; 83.07; 309.72} 0.2256 {113.20; 150.95; 240.70} {176.70; 195.50; 221.85} 0.2256
Lysine (Lys) {30.60; 35.85; 148.90} {44.80; 107.85; 735.23} 0.4117 {269.50; 362.60; 486.10} {260.43; 416.88; 487.98} 0.8513
3-Methyl-histidine (mHis) {38.55; 59.10; 89.85} {49.18; 58.20; 133.65} 0.5714 {26.05; 29.35; 37.75} {25.60; 37.98; 46.48} 0.5714
Ornithine (Orn) {27.00; 35.75; 58.10} {24.83; 31.75; 62.23} 0.7531 {112.40; 184.75; 247.85} {144.70; 191.10; 232.40} 0.8513
Phenylalanine (Phe) {27.45; 33.80; 44.10} {29.58; 61.98; 783.35} 0.5714 {160.10; 228.05; 266.40} {151.15; 268.45; 391.73} 0.5714
Sarcosine (Sarc) {54.66; 130.45; 241.49} {45.76; 626.97; 2190.96} 0.8513 {462.33; 814.47; 1302.42} {717.13; 981.58; 1148.66} 0.7531
Serine (Ser) {60.95; 89.10; 242.05} {97.85; 488.10; 1131.75} 0.4117 {135.90; 168.80; 310.90} {239.58; 335.98; 338.55} 0.3429
Threonine (Thr) {34.75; 48.40; 101.60} {42.20; 745.53; 1446.18} 0.2256 {143.85; 202.70; 392.80} {262.00; 363.98; 421.40} 0.4894
Tyrosine (Tyr) {30.05; 36.10; 56.50} {31.38; 55.60; 423.83} 0.5714 {130.85; 138.50; 212.70} {113.70; 151.88; 233.25} 0.8513
Citruline (Cit) {19.80; 19.95; 22.50} {19.28; 25.68; 31.85} 0.9495 {29.55; 43.00; 60.10} {26.20; 32.78; 40.38} 0.2256
Asparagine (Asn) {23.95; 28.30; 35.70} {23.28; 91.60; 214.35} 0.5714 {36.65; 51.35; 55.30} {54.05; 59.75; 78.10} 0.1419
Glutamine (Gln) {44.60; 57.25; 108.60} {46.73; 253.15; 834.65} 0.5714 {202.00; 274.75; 424.90} {405.30; 466.93; 557.18} 0.0396
Tryptophan (Trp) {11.90; 13.10; 14.80} {12.53; 16.68; 33.35} 0.4894 {15.20; 18.60; 21.85} {17.63; 19.70; 22.68} 0.5714
Aminopimelic acid (APA) {38.35; 38.37; 38.41} {38.38; 38.39; 38.41} 0.3429 {19.70; 19.70; 19.70} {19.60; 19.65; 20.10} 0.6608
Glycine-proline (dipeptide) (Gly-Pro) {37.69; 37.84; 39.55} {38.61; 39.07; 46.16} 0.1773 {19.10; 19.15; 19.30} {19.10; 19.23; 19.30} 0.7333
Thioproline (tPro) {37.60; 37.61; 37.65} {37.62; 37.64; 37.89} 0.4117 {19.90; 20.00; 20.05} {19.98; 20.13; 20.33} 0.1773

Data is presented as {1st quartile; median value; 3rd quartile}; cases in which p < 0.05 (U Mann–Whitney test) are marked in bold. The median value is expressed as µmol/L.