Table 4.
Cox proportional hazard models obtained by means of stepwise regression or backward elimination (maximum of 50 iterations).
Stepwise regression model | |||||||||
---|---|---|---|---|---|---|---|---|---|
− 2LogL | AIC | SBC | R2 | ||||||
25.98 | 29.98 | 30.77 | 0.77 | ||||||
Variable | Coefficient | SE | χ2 | p | − 95% CI | 95% CI | HR | − 95% CI HR | 95% CI HR |
SOFA (1) | − 0.5083 | 0.1883 | 7.2882 | 0.0069 | − 0.8773 | − 0.1393 | 0.6015 | 0.4159 | 0.8700 |
Glutamine (Gln) | − 0.0083 | 0.0040 | 4.4167 | 0.0356 | − 0.0161 | − 0.0006 | 0.9917 | 0.9840 | 0.9994 |
Backward elimination model | |||||||||
---|---|---|---|---|---|---|---|---|---|
− 2LogL | AIC | SBC | R2 | ||||||
15.04 | 25.04 | 27.03 | 0.91 | ||||||
Variable | Coefficient | SE | χ2 | p | − 95% CI | 95% CI | HR | − 95% CI HR | 95% CI HR |
APACHE II | 0.1977 | 0.1160 | 2.9022 | 0.0885 | − 0.0298 | 0.4251 | 1.2186 | 0.9707 | 1.5297 |
SOFA | − 1.3534 | 0.5261 | 6.6181 | 0.0101 | − 2.3846 | − 0.3223 | 0.2583 | 0.0921 | 0.7245 |
Glutamine (Gln) | − 0.0140 | 0.0068 | 4.2281 | 0.0398 | − 0.0273 | − 0.0007 | 0.9861 | 0.9731 | 0.9993 |
Septic shock: NO | − 2.2801 | 0.9862 | 5.3452 | 0.0208 | − 4.2130 | − 0.3472 | 0.0105 | 0.0002 | 0.4994 |
Sex: MALE | 1.7225 | 0.9765 | 3.1112 | 0.0778 | − 0.1915 | 3.6364 | 31.3410 | 0.6818 | 1440.6253 |
P-values < 0.05 and their corresponding hazard ratios (HR) are marked in bold. AIC, Akaike information criterion; SBC, Schwarz bayesian criterion; SE, standard error; HR, hazard ratio; CI, confidence interval, SOFA, sequential organ failure assessment; Gln, glutamine.