TABLE 4.

Multivariate Analysis for Events in Nonobstructive CAD (1% to 49% Stenosis Left Main or 1% to 69% Stenosis Any Coronary Artery)

	HR (95% CI)	p Value
Traditional CV risk plus CAD characteristics (using covariates with p < 0.20 from models 1 and 2) (n = 1,982)
ASCVD risk (continuous)	1.03 (1.02–1.05)	<0.001*
≥2 HRP (vs. <2 HRP)	2.25 (1.01–5.01)	0.046*
Mild/moderate stenosis (vs. minimal stenosis)	1.79 (1.04–3.08)	0.035*
CAC (continuous)†	1.00 (0.9998–1.0006)	0.235

Results are similar when using a full specified model that includes all variables (Supplemental Table 1).

^*Significant (p < 0.05).

^†Similar results are found when using log CAC instead of CAC.

ASCVD = atherosclerotic cardiovascular disease; CAC = coronary Artery Calcium; CAD = coronary artery disease; CI = confidence interval; CV = cardiovascular; HR = hazard ratio; HRP = high risk plaque; SIS = segment involvement score