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. 2021 Sep 24;12:713595. doi: 10.3389/fphar.2021.713595

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Copyright © 2021 Shimabukuro, Cataruci, Ishikawa, Oliveira, Kawamoto, Ando-Suguimoto, Albuquerque-Souza, Nicoli, Ferreira, de Lima, Bueno, da Silva, Silva, Messora, Camara, Simionato and Mayer.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mean and SD of weight gain in grams after 45 days of experimental period of C57Bl/6 mice submitted to different treatments: SHAM (negative control), P + B- (positive control), P-B+ (1101) (B. breve 110^1A), P + B+ (1101) (microbial consortium + B. breve 110^1A), P-B+ (1622) (B. bifidum 162^2A) and P + B+ (1622) (Microbial consortium + B. bifidum 162^2A). *Statistically significant difference in relation to negative control (SHAM), # Statistically significant difference in relation to positive control (P + B-). ANOVA, Tukey’s multiple comparison, p <0.05%. Data representative of two independent experiments (n = 8 mice/per group).