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. 2021 Sep 24;12:721775. doi: 10.3389/fphys.2021.721775

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Copyright © 2021 Xu, Xie, Zhao, Wu, Wang and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Morphological analyses of mandibles from 3.2 kb Col1^Lin Tgfβr2 conditional knockout (cKO) mice at the cellular level. (A) Masson's trichrome staining showed no apparent change of alveolar bone mass in the cKO mice (right). (B) Polarized light images displayed a similar collagen fiber distribution of periodontal ligament (PDL) in the control and cKO group (right). (C) The 3.2 kb Col1^Lin tracing images revealed largely similar red cell numbers in both the control and the cKO alveolar bone. AB, alveolar bone; PDL, periodontal ligament; D, dentin.