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. 2021 Sep 24;11:721644. doi: 10.3389/fonc.2021.721644

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Copyright © 2021 Cai, Zhang, Hu, Hu, Yang, Qiu and Chu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Volcano plots and heatmap plots of DEGs between the expression of CDT1^high and CDT1^low in HCC samples. (A) The volcano plot described 3755 DEGs (|log2fold change| > 1 and adjusted p-value < 0.05). (B) The histogram showing the number of up-regulated or down-regulated genes. (C, D) The heatmaps depicted the expression of 15 significant upregulated and downregulated genes in HCC samples with CDT1^high and CDT1^low expression. *p < 0.05, ***p < 0.001.