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. 2021 Sep 24;11:721644. doi: 10.3389/fonc.2021.721644

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Copyright © 2021 Cai, Zhang, Hu, Hu, Yang, Qiu and Chu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Results of enrichment analysis. (A, B) GO and KEGG enrichment results of CDT1-related DEGs (15 most significant upregulated and 15 most significant downregulated genes in HCC samples with CDT1^high and CDT1^low expression). (C–H) Gene set enrichment plots of (C) DNA replication, (D) cell cycle checkpoints, (E) mitotic prometaphase, (F) integrated cancer pathway, (G) DNA repair, and (H) cellular senescence with high CDT1 expression from GSEA.