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. 2021 Sep 24;11:721644. doi: 10.3389/fonc.2021.721644

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Copyright © 2021 Cai, Zhang, Hu, Hu, Yang, Qiu and Chu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A, B) Interaction network of CDT1 and their most similar genes on GeneMANIA (A) and STRING (B) datasets. (C) Heatmap of the expression of MCM family genes in HCC samples with CDT1^high and CDT1^low expression. (D–G) Scatter plot results using Spearman correlation analysis between MCMs and CDT1 at the transcriptional level. ***p < 0.001.