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. 2021 Sep 24;11:721644. doi: 10.3389/fonc.2021.721644

Table 2.

Cox regression analyses of variables for OS and DSS in LIHC patients.

Characteristics OS DSS
Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
Age (>60 vs. <=60) 1.205 (0.850-1.708) 0.295 0.846 (0.543-1.317) 0.458
Gender (Male vs. Female) 0.793 (0.557-1.130) 0.200 0.813 (0.516-1.281) 0.373
Race (Non-Asian vs. Asian) 1.341 (0.926-1.942) 0.121 1.500 (0.927-2.427) 0.098 2.671 (1.183-6.030) 0.018
Pathologic stage (Stage II& III& IV vs. I) 2.090 (1.429-3.055) <0.001 1.772 (1.180-2.661) 0.006 2.909 (1.718-4.925) <0.001 1.951 (0.973-3.914) 0.060
Residual tumor (R1&R2 vs. R0) 1.604 (0.812-3.169) 0.174 1.678 (0.728-3.870) 0.224
AFP (ng/ml) (>400 vs. <=400) 1.075 (0.658-1.759) 0.772 0.867 (0.450-1.668) 0.668
Child-Pugh grade (B&C vs. A) 1.643 (0.811-3.330) 0.168 2.560 (1.123-5.834) 0.025 2.848 (1.195-6.788) 0.018
Fibrosis ishak score (3/4&5/6 vs. 0&1/2) 0.740 (0.445-1.232) 0.247 0.660 (0.340-1.279) 0.218
Vascular invasion (Yes vs. No) 1.344 (0.887-2.035) 0.163 1.277 (0.707-2.306) 0.418
Tumor status (With tumor vs. Tumor free) 2.317 (1.590-3.376) <0.001 1.809 (1.210-2.703) 0.004 2.389 (1.760-2.872) 0.094
CDT1 (High vs. Low) 1.916 (1.347-2.724) <0.001 1.588 (1.067-2.363) 0.023 2.297 (1.452-3.634) <0.001 2.609 (1.323-5.147) 0.006

Bold values indicate significant p-values.