Table 3.
Diagnostic performance of RP-EBUS-TBLB according to the size of PPLs
| Parameter | <20 mm (n=159) | 20–30 mm (n=188) | >30 mm (n=260) | Diagnostic performance (n=607) |
|---|---|---|---|---|
| True-positive, n | 54 | 102 | 149 | 305 |
| True-negative, n | 33 | 45 | 79 | 157 |
| False-positive, n | 0 | 0 | 0 | 0 |
| False-negative, n | 72 | 41 | 32 | 145 |
| EBUS pathologic result false negative, n | 15 | 12 | 8 | 35 |
| Indefinite final diagnosis, n | 19 | 8 | 13 | 40 |
| Invisible on EBUS | 38 | 21 | 11 | 70 |
| Sensitivity, % | 42.9 | 71.3 | 82.3 | 67.8 |
| Specificity, % | 100.0 | 100.0 | 100.0 | 100.0 |
| PPV, % | 100.0 | 100.0 | 100.0 | 100.0 |
| NPV, % | 31.4 | 52.3 | 71.2 | 52.0 |
| Diagnostic accuracy | 54.7 | 78.2 | 87.7 | 76.1 |
RP-EBUS-TBLB: radial probe endobronchial ultrasound-guided transbronchial lung biopsy; PPL: peripheral pulmonary lesion; PPV: positive predictive value; NPV: negative predictive value.