Table 4.
Factors affecting diagnostic success of RP-EBUS-TBLB using a GS without fluoroscopy for diagnosing PPLs
| Diagnostic success (n=462) | Diagnostic failure (n=145) | Univariable analyses |
Multivariable analyses |
||||
|---|---|---|---|---|---|---|---|
| Odds ratio (95% confidence interval) | p-value | Odds ratio (95% confidence interval) | p-value | ||||
| Age, yr | 68.2±12.0 | 66.6±11.8 | 1.01 (0.99–1.03) | 0.170 | - | - | |
| Male sex | 300 (64.9) | 95 (65.5) | 1.03 (0.69–1.52) | 0.898 | - | - | |
| Size, mm | 32.8±16.2 | 23.5±13.7 | 1.05 (1.04–1.07) | <0.001 | - | - | |
| ≥20 | 375 (81.2) | 73 (50.3) | 4.25 (2.85–6.35) | <0.001 | 2.06 (1.27–3.33) | 0.003 | |
| <20 | 87 (18.8) | 72 (49.7) | 1.00 | - | - | - | |
| Bronchus sign in chest CT | - | - | - | - | - | - | |
| Positive | 399 (86.4) | 77 (53.1) | 5.59 (3.67–8.52) | <0.001 | 2.30 (1.40–3.78) | 0.001 | |
| Negative | 63 (13.6) | 68 (46.9) | 1.00 | - | - | - | |
| Characteristic | |||||||
| Solid | 419 (90.7) | 111 (76.6) | 3.00 (1.82–4.90) | <0.001 | 2.40 (1.31–4.41) | 0.005 | |
| Non-solid | 43 (9.3) | 34 (23.4) | 1.00 | - | - | - | |
| EBUS image | |||||||
| Within | 380 (82.3) | 45 (31.0) | 10.30 (6.73–15.75) | <0.001 | 6.98 (4.38–11.12) | <0.001 | |
| Adjacent to the lesion or outside | 82 (17.7) | 100 (69.0) | 1.00 | - | - | - | |
Values are presented as mean±standard deviation or number (%) unless otherwise indicated.
RP-EBUS-TBLB: radial probe endobronchial ultrasound-guided transbronchial lung biopsy; GS: guide sheath; PPL: peripheral pulmonary lesion; CT: computed tomography; Solid: solid+cavity+consolidation; Non-solid: part solid+ground-glass opacity.