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. 2021 Sep 24;12:716684. doi: 10.3389/fphar.2021.716684

FIGURE 9.

FIGURE 9

Hig regulated the proteins expressed in Nox2/ROS/TRP/P38 MAPK/NF-ĸB signaling pathway. (A) The control and t-BHP-exposed RSC96 were collected and analyzed by WB for expression level of Nox2, TRPA1, TRPV1, p38 MAPK, p-p38 MAPK, and p-NF-ĸB. (B) The DRG tissues from sham-operated and CCI surgery were collected and analyzed by WB for expression level of Nox2, TRPA1, TRPV1, p38 MAPK, p-p38 MAPK, and p-NF-ĸB. GAPGH served as internal control. The results are presented as mean ± SEM, n = 3. #p < 0.05, ##p < 0.01, and ####p < 0.0001 vs. the control group. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001 vs. the model group.